A newly built warship will take its first step towards handover to the Royal Navy on Friday as it leaves the yard where it was constructed.
The Type 45 Destroyer Duncan will leave BAE System's Scotstoun yard in Glasgow and journey to Portsmouth Naval Base where it will be officially commissioned.
It marks the completion of a six ship contract with the Ministry of Defence.
Glasgow City Council leader Gordon Matheson will be among those attending the send off.
Labour has suggested that future Navy contracts would be threatened by independence.
Defence spokesman Jim Murphy MP said: "Duncan is the latest formidable ship from a river that has built the world's ships for so many years.
"Times have changed and much of that work now takes place in cheaper yards in Asia. We want to keep the Clyde as a working river and that will rely on winning future Royal Naval orders. The big threat to the Clyde is 2014 and the SNP plans for independence.
"The Royal Navy doesn't build complex warships in foreign shipyards. If Scotland was to leave the UK we would also be leaving the Royal Navy. Scotland would be a foreign country to the Royal Navy and thousands of the Clyde's shipbuilding jobs would be lost."
However, the SNP objected to such claims. A spokesman for the party said: "This is rank hypocrisy from the Labour Party, that spent its years in office running Scotland's defence forces down and destroying 11,000 defence jobs in Scotland over the last decade.
"It is not the London government that makes Scotland's yards successful, it is the second-to-none Scottish skills base and technical expertise that brings orders to the yards from Westminster and around the world, and that will continue after independence."